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|n acetylcysteine and vitamin c||$13.99|
KEGG: Kyoto encyclopedia of genes and genomes. Since only 0. Always consult your healthcare provider. Evidence has shown that apoptosis induced by ROS was accompanied by caspase-3 activation, whereas inhibition of caspase-3 blocked apoptosis
Therefore NAC acetylcysteine acetylysteine be attractive in antioxidant therapy of inflammatory disorders of the lung.
This study aimed to investigate the use of antioxidant therapy with NAC in chronic bronchitis. The treatment consisted of either mg Amd athlon ii x2 b24 vs i3 bid, vitamin Vitamin C bid, a combination of those two substances using the same dosage or a placebo-preparation. The release of reactive oxygen species from isolated neutrophilic granulocytes and mononuclear cells was quantified before treatment and after three months using wcetylcysteine primary outcome parameter.
Furthermore cellular glutathione content of these inflammatory cells was quantified spectrometrically. In addition, leukocyte-count and erythrocyte sedimentation rate as well as spirometry and a standardized symptom-based questionnaire were used to monitor the clinical efficacy.
RESULTS: None of the above qnd were able to significantly reduce the release of reactive oxygen species from the examined population of inflammatory cells. They and failed to increase intracellular glutathione-levels. Concordantly, no changes in spirometry and the results of the symptom-based questionnaire were found.
Possible reasons may nad a lack of antioxidant deficiency in these patients and negative feedback mechanisms of the glutathione-system.
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